C of C is the chamber of Commerce. Other definition is following.
"C of C" in the travel, transport and hotel context could be an abbreviation of "Certificate of Compliance" which is a document that certifies that a company or organization complies with a certain set of rules, regulations or standards.
For example, a hotel might have to obtain a certificate of compliance from a local authority that verifies that the hotel meets the necessary health and safety standards or fire codes. Similarly, a transportation company might have to obtain a certificate of compliance from a government agency that verifies that the company meets safety and maintenance standards for its vehicles.
Another example, a travel agency might have to obtain a certificate of compliance from an international standard organization that verifies that the agency meets the standard for the quality of their services, such as providing accurate information, protecting clients' personal information, and resolving complaints efficiently.
It could also refer to something else depending on the context and specific industry, please provide more information if the answer doesn't match your question.